Indian Journal of Psychological Medicine
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Year : 2012  |  Volume : 34  |  Issue : 4  |  Page : 391-393

Suicidality and Suicide Attempt in a Young Female on Long-Term Sertraline Treatment

1 Department of Clinical & Experimental Pharmacology, Calcutta School of Tropical Medicine, Kolkata, West Bengal, India
2 Senior Research Fellow, National Institute of Cholera and Enteric Diseases, Kolkata, West Bengal, India
3 Department of Pharmacology, Calcutta Medical College, Kolkata, West Bengal, India

Correspondence Address:
Ranjita Santra
Department of Clinical and Experimental Pharmacology, Calcutta School of Tropical Medicine, Kolkata, West Bengal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0253-7176.108230

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A 22-year-old woman who was on sertraline 50 mg oral tablets once daily for 2 years for treatment of major depression took 30 such tablets (1500 mg) in a fit of rage, with a suicidal intent. She presented to the Emergency Department of a Tertiary Care Hospital with tachycardia, tachypnea, hypertension, tremors, agitation, confusion, vomiting, and hyperthermia. The patient was admitted and treated symptomatically, and sertraline therapy was discontinued. The unwanted effects subsided within 48 h and she recovered uneventfully within 72 h. This case report describes an unsuccessful attempt of suicide with sertraline overdose in a patient on long-term sertraline therapy and underlines the importance of close monitoring of such patients.

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