Indian Journal of Psychological Medicine
  Home | About Us | Editorial Board | Search | Ahead of print | Current Issue | Archives | Instructions | Contact | Advertise | Submission | Login 
Users Online: 1060 
Wide layoutNarrow layoutFull screen layoutHome Print this page Email this page Small font sizeDefault font sizeIncrease font size
CASE REPORT
Year : 2015  |  Volume : 37  |  Issue : 2  |  Page : 226-229

An extremely rare association of Dyggve-Melchior-Clausen syndrome with mania: Coincidence or comorbidity


1 Department of Psychiatry, King George's Medical University, Lucknow, Uttar Pradesh, India
2 Department of Psychiatry, Institute of Human Behavior and Allied Sciences (IHBAS), Delhi, India

Correspondence Address:
Dr. Sujita Kumar Kar
Lecturer, Department of Psychiatry, King George's Medical University, Lucknow, Uttar Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0253-7176.155644

Rights and Permissions

Dyggve-Melchior-Clausen syndrome is a progressive spondylo-epi-metaphyseal dysplasia associated with mental retardation, characterized by a triad of skeletal deformities (short trunk dwarfism, scoliosis, microcephaly, and limb deformities), facial dysmorphism, and intellectual disability. It an extremely rare condition. Till now, there was no evidence of association of Dyggve-Melchior-Clausen Syndrome with mood disorder. This case report highlights the extremely rare association of Dyggve-Melchior-Clausen syndrome with bipolar affective disorder. The patient had responded well to the combination of mood stabilizer and antipsychotics (sodium valproate and risperidone). To the best of author's knowledge, this is the first case report depicting such association. Both Dyggve-Melchior-Clausen syndrome and bipolar affective disorder are associated with 18q chromosome. This background information raises the possibility of co-morbid association of two disorders rather than a chance association due to genetic linkage.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1486    
    Printed26    
    Emailed0    
    PDF Downloaded45    
    Comments [Add]    

Recommend this journal