Indian Journal of Psychological Medicine
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CASE REPORT
Year : 2016  |  Volume : 38  |  Issue : 1  |  Page : 62-64

Rapid resolution of grief with IV infusion of ketamine: a unique phenomenological experience


1 Department of Psychiatrist, Spandana Nursing Home, Bangalore, Karnataka, India
2 Clinical Research Coordinator, Spandana Nursing Home, Bangalore, Karnataka, India
3 DNB Resident, Spandana Nursing Home, Bangalore, Karnataka, India

Correspondence Address:
Mahesh Ramanna Gowda
Spandana Health Care, No. 236/2, 29th Main, 5th Block, Nandini Layout, Bangalore - 560096, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0253-7176.175121

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Ketamine, a primarily FDA-approved anaesthetic agent is also used as recreational drug. Based on preclinical findings and later the clinical observations it is noted to have rapid antidepressant effect due to its mechanisms related to NMDA antagonism. In spite of established evidence of ketamine being effective in depression with significant role in treatment resistant cases as well, there was absolute dearth of literature regarding its utility in grief-related disorders. In this context we present a case of 28-year-old graduate male who presented to us in complicated grief following death of his wife due to obstetric complications. With the patient and immediate family members consenting for use of ketamine as off-label use, patient had single IV infusion of ketamine following which he had unique phenomenological experience ultimately resolving his grief in few minutes. Through this case we highlight the enormous therapeutic promise of ketamine in complicated grief.


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