Indian Journal of Psychological Medicine
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Year : 2017  |  Volume : 39  |  Issue : 5  |  Page : 665-667

Opioid withdrawal presenting as delirium and role of buprenorphine: A case series

1 Antara Psychiatric Centre, Sri Aurobindo Seva Kendra, Kolkata, West Bengal, India
2 Department of Psychology, Kumaun University, Nainital, Uttarakhand, India
3 Department of General Medicine, Sri Aurobindo Seva Kendra, Kolkata, West Bengal, India

Correspondence Address:
Sourav Das
Antara Psychiatric Centre, P. O. Dakhshin Gobindapur, P.S. Baruipur, Dist. 24 Pargana (South), Kolkata - 700 145, West Bengal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0253-7176.217027

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Opioid withdrawal is very rarely characterized by delirium unlike alcohol or benzodiazepine withdrawal. PubMed search through October 2016 reveals only two case series on delirium as feature of withdrawal in opioid dependence syndrome. We report two cases of opioid withdrawal (heroin) presenting with delirium when low-dose buprenorphine (2 mg/day) was added. Both the cases had no other substance abuse history and nil contributory past and family history. Both of them were improved after increasing the buprenorphine dosage to 6–8 mg/day. The possibility of delirium as a part of withdrawal symptom or as a phenomenon induced by buprenorphine or due to impurities in the heroin used is discussed.

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