Indian Journal of Psychological Medicine
  Home | About Us | Editorial Board | Search | Ahead of print | Current Issue | Archives | Instructions | Contact | Advertise | Submission | Login 
Users Online: 284 
Wide layoutNarrow layoutFull screen layoutHome Print this page Email this page Small font sizeDefault font sizeIncrease font size
Year : 2019  |  Volume : 41  |  Issue : 1  |  Page : 99-100

Multiple testing and protection against a type 1 (false positive) error using the Bonferroni and Hochberg corrections

Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India

Correspondence Address:
Dr. Chittaranjan Andrade
Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore - 560 029, Karnataka
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/IJPSYM.IJPSYM_499_18

Rights and Permissions

In a given study, if many related outcomes are tested for statistical significance, one or more outcomes may emerge significant at the P < 0.05 level not because they are truly significant in the population but because of chance. The larger the number of statistical tests performed, the greater the risk that some of the significant findings are significant because of chance. There are many ways to protect against such false positive or Type 1 errors. The simplest way is to set a more stringent threshold for statistical significance than P < 0.05. This can be done using either the Bonferroni or the Hochberg correction. Using the Bonferroni correction, 0.05 is divided by the number of statistical tests being performed and the result is set as the critical P value for statistical significance. Using the Hochberg correction, the P values obtained from the different statistical tests are arranged in descending order of magnitude, and each P value is assessed for significance against progressively more stringent levels for significance. The Bonferroni and Hochberg procedures are explained with the help of examples.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded30    
    Comments [Add]    

Recommend this journal